Through their many and varied metabolic functions mitochondria power life paradoxically mitochondria also have a central role in apoptotic cell death upon induction of mitochondrial apoptosis . Mitochondria and cell death part of the cell death in biology and diseases series is invaluable reading for graduate students researchers and clinicians in the fields of neuroscience oncology gastroenterology and hepatology as well as those interested in the study of mitochondria and cell biology. They generate the majority of our adenosine triphosphate atp the energy currency of the cell mitochondria are also involved in other tasks such as signaling between cells and cell death . Genetic and pharmacological manipulations indicate that cell death is an important component in the pathogenesis of both diseases cells die primarily by apoptosis or necrosis and autophagy has been associated with cell death apoptosis has long been recognized as a highly regulated process. Start studying cell biology diseases learn vocabulary terms and more with flashcards games and other study tools search a defect in lamin a c which leads to fragile nuclear lamina and cells death eventually leads to congestive heart failure mitochondria painless bilateral visual failure missense mutation in a subunit of
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