The identification of a patient at high risk of fracture should be followed by evaluation for factors contributing to low bone mass skeletal fragility falls and fractures components of the evaluation include a bone density test osteoporosis directed medical history and physical exam laboratory studies and possibly skeletal imaging a bone density test with dual energy x ray . Secondary osteoporosis is caused by other health conditions 2 up to 30 of osteoporosis cases in postmenopausal women are estimated to be from a secondary cause10 the estimate climbs to greater . Osteoporosis nonclinical evaluation of drugs intended for treatment guidance for industry guidance for industry june 2016 download the draft guidance document
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